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Our research in the Enteric Bacterial Pathogens Laboratory is aimed at improving food safety and enhancing the health and welfare of farmed animals. We do this by dissecting, at a molecular level, why it is that Salmonella, Campylobacter and enterohaemorrhagic E. coli cause disease. These bacteria collectively caused 67,402 laboratory-confirmed cases of acute diarrhoeal illness in people in the UK in 2006. Such infections of people are frequently acquired through the food chain and the environment from animals. Towards controlling these bacteria on farms, we have a mix of fundamental, strategic and applied projects that use knowledge of the role of bacterial and host factors in the disease process to develop and test novel methods of disease control. We do our research at all levels, from molecules to target farm animals. We also do award-winning work to reduce, refine or replace animals in research. We are also studying other animal diseases, including melioidosis [1] and avian colibacillosis.